The potential of impulse oscillometry in lung function assessment in children after allogeneic hematopoietic stem cell transplantation

The article analyzes the potential of using impulse oscillometry in diagnosis respiratory disorders children with oncological and hematological diseases after allogeneic hematopoietic stem cell transplantation (HSCT). study was approved by Independent Ethics Committee Scientific Council Dmitry Rogachev National Medical Research Center Pediatric Hematology, Oncology Immunology Ministry Healthcare Russian Federation. A comparative analysis parameters spirometry before on Days 30, 90, 180 360 HSCT carried out. It revealed that pulmonary ventilation function impairments are quite common this group patients, worsening significantly month 3 follow-up. An increase reactance at a frequency 5 Hz is one earliest signs impaired function, which can be used for timely complications HSCT.